Inspired by the natural microstructure and chemical composition of bone, this study built in situ micro-nano gradient bioactive coatings containing trace elements on 3D-printed porous titanium alloy scaffolds. This functional surface can autonomously regulate the local immune microenvironment through a dual mechanism of morphology control and ion release, simultaneously promoting vascularization, innervation, and bone formation, offering new ideas for designing smart bone repair implants.

Original Source:

Advanced Composites and Hybrid Materials

Pub Date: 2026-09-26

DOI: 10.1007/s42114-026-02095-w

Dongmei Yu, Zhen Tang, Tonglei Yang, Shuo Guo, Shusen Bao, Chenyu Li, Qi Wu, Changchen Chen, Yingxiang Liu, Xiaokang Li, Hai Huang, Hao Wu, Zheng Guo

We focus on customizing functional nanomedicine materials and can develop them according to experimental needs, controlling material structure, particle size, and surface modifications, along with full characterization support.

Our plans allow for repeated optimization and full technical support, serving research projects in targeted delivery, bioimaging, nanodiagnostics, and therapy. Feel free to provide evaluation criteria.

Engineer Zhang: 17715390137  Engineer Chen: 18914047343