The latest research progress of black phosphorus-from unique structure to biomedical applications

This article introduces the latest research progress of black phosphorus in the field of biomedicine by Chen Tongkais group at Guangzhou University of Chinese Medicine and Zhang Hans group at Shenzhen University, published in the Journal of Innovative Optical Health Sciences.

Black Phosphorus as a Versatile Nanoplatform: From Unique Properties to Biomedical Applications.

Sha Xiong, Xiaojia Chen, Yao Liu, Taojian Fan, Qi Wang, Han Zhang, Tongkai Chen








Research Background



Since Black Phosphorus (BP) was first reported in 2014, it has attracted attention due to its unique structure and performance (excellent photo-thermal performance, ultra-high drug-carrying capacity, good biocompatibility and degradability). The majority of scientific research workers devote themselves to experimental and applied research. However, compared with other two-dimensional materials, research on black phosphorus is still in its infancy. Therefore, a comprehensive understanding of the properties of black phosphorus, analysis of existing biomedical research directions, and exploration of more unknown possible biomedical applications of black phosphorus will lay a theoretical foundation for the clinical transformation of black phosphorus.






brief introduction



This article provides a comprehensive review of black phosphorus, from the unique structural properties of black phosphorus, to the preparation methods and biomedical applications of black phosphorus (for example, bioimaging, tumor treatment, drug delivery, 3D printing, neurodegenerative diseases, and biosensors) Etc.), the related research results are introduced in detail. Finally, the challenges and application prospects of black phosphorus are further discussed.






Graphic guide



The black phosphorous structure is similar to graphene, which is hexagonal layered, but its wrinkled structure gives it unique properties. Black phosphorus has good mechanical, electrical, thermal and optical properties. A variety of methods for preparing black phosphorus have been developed, and the related technologies are relatively mature, which can meet the needs of experiments and moderate production. The biological safety and good degradability of black phosphorus are the basis for its application in the field of biomedicine. In recent years, the application of black phosphorus in biomedicine has continued to heat up, showing the immeasurable application prospects of black phosphorus in the future.




Figure 1 The structure of black phosphorus






Figure 2 Basic properties of black phosphorus

Director of Operations: Zhang Xiaolong


Figure 3 Preparation method of black phosphorus




Figure 4 Biomedical applications of black phosphorus






Introduction to PI




Chen Tongkai
(Corresponding author of this article)

Associate Professor, Guangzhou University of Chinese Medicine

Chen Tongkai, Guangzhou University of Traditional Chinese Medicine Xinglin introduced talents, associate professor, masters tutor, engaged in pharmaceutics and biomedical applications of nanomaterials. The main research results are published in Advanced Drug Delivery Reviews, Biomaterials, Nano-Micro Letters, Journal of Controlled Release, ACS Applied Materials & Interfaces and other internationally renowned journals. Presided over and participated in many scientific research projects such as the National Natural Science Foundation of China, Guangdong Basic and Applied Basic Research Fund, Guangdong Natural Science Foundation, and Guangdong Medical Research Fund. Served as a reviewer for many international journals such as Advanced Materials, ACS Nano, Biomaterials, Small, Nanoscale, and participated in the editing of monographs and teaching materials such as "Chinese Pharmaceutical Excipients" and "Pharmacy".




Zhang Han
(Corresponding author of this article)

Professor of Shenzhen University

Professor Zhang Hans main research fields are the research of two-dimensional materials nonlinear ultrafast photonics and devices and biophotonics technology. In the past five years, he has published more than 60 papers in the first district of the Chinese Academy of Sciences as corresponding authors, including PNAS, Nature Communications, Phys. Reports, etc. The papers have been cited more than 16,000 times, with an H-index of 62. Among them, there are more than 40 highly cited papers by ESI, and two papers have been selected as Chinas 100 most influential international academic papers.






Journal Introduction



"Journal of Innovative Optical Health Science" (JIOHS) is headed by the Ministry of Education, hosted by Huazhong University of Science and Technology, and jointly published by the Singapore World Science Press and the editorial office of Huazhong University of Science and Technology "Innovative Optical Health Science (English)". The editor-in-chief of the journal is Academician Luo Qingming, President of Hainan University and Director of Wuhan Optoelectronics National Research Center of Huazhong University of Science and Technology. JIOHS journals have been indexed by SCI (IF1.661), Ei, Scoops and other databases, and are open access (OA) journals. The journal was selected as Project D of Chinas Science and Technology Journals Impact Improvement Plan in 2018.

The purpose of the JIOHS journal is to publish new theories, new developments, and new results in the field of biomedical photonics, promote academic exchanges at home and abroad, promote the research and application of photonics technology in the field of biomedicine, and improve my countrys scientific research in this field. international influence. The content includes but not limited to: photon therapy and diagnostics, optical clinical application technology and systems, tissue optics, laser biological tissue interaction and tissue engineering, biomedical spectroscopy, advanced microscopy and imaging technology, nanobiophotonics and Optical molecular imaging, multi-mode hybrid biomedical imaging, micro-nano processing and medical micro-systems.

For more journal details, see:

http://www.worldscientific.com/worldscinet/jiohs




Article from: JIOHS JIOHS
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