Application of graphene oxide (GO) in the field of regenerative medicine

In the previous article, we talked about graphene, which has a wide range of applications in the biomedical field and can be used as a carrier for targeted drug therapy.



Graphene atomic scale structure



In addition to graphene, its derivative forms have also been extensively studied in the past decade.



These derivatives have many different roles in the field of biomedicine, including, but not limited to, preparation of drug delivery carriers, as biosensors and diagnostic tools.



According to its future development prospects, the most researched one is graphene oxide (GO) and its reduction, reduced graphene oxide (rGO).



The experimental results show that, among them, the research and application of 3D stent system based on GO and rGO are very promising.


Graphene oxide structure



The 3D stent system can help solve some of the problems that limit the development of regenerative medicine, enabling preclinical research to be applied.



At present, the application of GO and rGO has been developed in the research of regenerative medicine and tissue engineering of bone, heart and nerve tissue.



Why does graphene oxide have a good application prospect?



It turns out that after the oxidation of graphene, the hydrophilicity of the surface will increase, and at the same time it will produce abundant functional groups, such as hydroxyl, carboxyl, carbonyl, phenol, lactone, quinone, and epoxy groups.



Regenerative Medicine



The existence of these oxygen-containing groups greatly changes the properties of graphene oxide, promotes the formation of stable dispersions in aqueous media and other polar solvents, and contributes to biochemical and biological coupling reactions on the substrate and edges. Happened created perfect conditions.



These reactions can promote the interaction of the graphene oxide surface with proteins, antibodies and DNA fragments, so that the combined products have new functions required by biomedicine.