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This paper was published in "Advanced Functional Materials". The research aimed to address the issues of high mechanical stiffness, poor biocompatibility, and unstable electrical signals of traditional neural interface materials when treating peripheral nerve injuries. A new type of hydrogel-liquid metal composite double-layer neural interface was proposed. Through structural design and material integration, this interface achieved gentle attachment to neural tissues, stable electrical coupling, and long-term biocompatibility. It was successfully verified in animal models in terms of its potential in neural signal recording, electrical stimulation regulation, and recovery of closed-loop movement functions. Innovation Points
01 Structural Innovation: Bionic Double-Layer Design
By combining highly conductive flexible electrodes with bio-adhesive hydrogels, a "electrolyte-ion" conductive double-layer with both electrical functionality and interface conformality is constructed, achieving mechanical matching of the neural interface and efficient signal transmission.
02 Material Performance Breakthrough: Dynamic Adaptive Characteristics
The material system exhibits excellent stretchability, self-repairing ability, and stress relaxation behavior, which can adapt to the physiological activities of neural tissues and avoid tissue damage or signal interruption caused by mechanical mismatch.
03 "Intelligent Staying" Carrier Platform Not only does it achieve stable reading and writing of neural signals, but it also integrates with external execution devices to form a "sensing-stimulating-feedback" closed-loop system. This has verified the feasibility of motor function reconstruction at the animal level.
Journal Name: Advanced Functional Materials
Publication Date: March 8, 2026
DOI: 10.1002/adfm.202523385 R&D Team: Yewon Kim, Kyoungryong Kim, Jaehyon Kim, Heewon Choi, Mikyung Shin, Donghee Son
