registered   |   log in
  中文

Academic Frontier

 
contact us

hotline:

17715390137

Tel/Wechat:

  18101240246 (Technology)

0512-68565571

Emailmxenes@163.com (Sales Engineer)bkxc.bonnie@gmail.com

Scan the code to follow or search the official account on WeChat: 

2D Materials Fronrier After paying attention, 

click on the lower right corner to contact us, 

Enter enterprise WeChat.

Professional Services Online

Academic Frontier
position: home > Academic Frontier > COFs Biomedicine

Qu Xiaogang/Ren Jinsong Angew from Changchun Institute of Applied Chemistry: Biomimetic construction of MOF@COF nanozyme with pseudopod-like surface to inhibit bacteria

source:beike new material Views:5796time:2020-11-04 QQ Academic Group: 1092348845

Many MOFs have the function of mimicking enzymes, but due to their low catalytic activity, their catalysis and therapeutic effects are often unsatisfactory. Researcher Qu Xiaogang and Researcher Ren Jinsong, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, used inspiration from nature to design a MOF@COF nano-enzyme with high-efficiency peroxidase mimicking activity.




Key points of this article:

(1) The nanoenzyme takes the metal node of the MOF as the active center, and the COF structure that is subsequently grown will generate a multi-level nano-cavity to form a suitable pore environment near the active site, which can enrich and activate the substrate molecules, thereby enhancing Inhibition of bacteria.




(2) In addition, the pseudopod-like surface of COFs enables the system to effectively capture bacteria, thereby further enhancing the therapeutic efficiency of the nanoenzyme. In summary, this research can not only promote the development of new nanoenzymes, but also broaden the biological applications of MOF/COF-based hybrid materials.




references:

Lu Zhang. et al. Nature-Inspired Construction of MOF@COF Nanozyme with Active Sites in Tailored Microenvironment and Pseudopodia-like Surface for Enhanced Bacterial Inhibition. Angewandte Chemie International Edition. 2020

DOI: 10.1002/anie.202012487

https://onlinelibrary.wiley.com/doi/10.1002/anie.202012487


Source of information: Fantastic Object Theory

This information is from the Internet for academic exchanges. If there is any infringement, please contact us and delete it immediately


 

Reminder: Beijing Beike New Material Technology Co., Ltd. supplies products only for scientific research, not for humans
All rights reserved © 2019 beijing beike new material Technology Co., Ltd 京ICP备16054715-2号
advisory
phone
Email:mxenes@163.com
Tel:+86-17715390137
scan

scan
WeChat